Prochiral


In chemistry, prochiral molecules can be converted from achiral to chiral in a single step.[1]

If two identical substituents are attached to an ''sp''3-hybridized atom, the descriptors pro-R and pro-S are used to distinguish between the two. Replacing the pro-R substituent results in an R chirality center at the original sp<sup>3</sup>-hybridized atom, and vice versa.

A trigonal planar sp<sup>2</sup>-hybridized atom can be converted to a chirality center when a substituent is added to the re or si face of the molecule. <br clear="both">

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